Is ciprofloxacin safe during pregnancy

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  1. Natalia_Fedorova New Member

    Is ciprofloxacin safe during pregnancy


    Cipro (generic name: ciprofloxacin) is classified as an antibacterial drug, which is an antibiotic. Antibacterial drugs like Cipro are used to treat bacterial infections. Ciprofloxacin may be used to treat infections in people who have Crohn's disease. Some uncommon but serious side effects from Cipro include difficulty breathing or swallowing, sunburn or blistering, seizures or convulsions, and tendinopathy/tendon rupture. If you experience any of these symptoms call your doctor immediately. Cipro may also cause sensitivity to sunlight (including tanning beds or lamps). Reactions can include sunburn, skin rash, redness, and itching. Pregnant women strive to be as healthy as possible by watching what they eat, drink, and do with their bodies to ensure a safe, and healthy baby. Many expectant moms are hesitant to take antibiotics during pregnancy, although they're more vulnerable to getting bacterial infections, specifically UTIs. Now, researchers at the University of Montreal in Quebec have found their fears are validated: antibiotic use is linked to a higher risk of miscarriage, or spontaneous abortions, in early pregnancy., Berard and her colleagues found these five common antibiotics, including macrolides, quinolones, tetracyclines, sulfonamides and metronidazole, posed the greatest risk of miscarriage during the early stages of pregnancy. The average gestational age for miscarriage was 14 weeks of pregnancy; women who miscarried were more likely to be older, living alone, and have multiple health issues and infections. The researchers accounted for this before finalizing their results."Although antibiotic use to treat infections has been linked to a decreased risk of prematurity and low birth weight in other studies, our investigation shows that certain types of antibiotics are increasing the risk of spontaneous abortion, with a 60% to two-fold increased risk," said Dr. Anick Berard, author of the study, and Faculty of Pharmacy at the University of Montreal, in a statement. Data from the Quebec Pregnancy Cohort from 1998 to 2009 revealed over 8,702 cases were clinically detected as spontaneous abortions among women between the ages of 15 and 45 years.

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    Some antibiotics are OK to take during pregnancy, while others are not. Safety depends on various factors, including the type of antibiotic, when. Therefore, interrupting breastfeeding during ciprofloxacin treatment appears. Relative infant dose RID is the key parameter when considering the safety of. by the Research Leadership for Better Pharmacotherapy during Pregnancy and. Oct 27, 2018. Some antibiotics should not be used during pregnancy, because of their effects. Both ciprofloxacin and levofloxacin have been assigned pregnancy. Nitrofurantoin is safe and effective; however, poor tissue penetration has.

    ABSTRACT QUESTION My patient has a urinary tract infection and is currently breastfeeding her 9-week-old son. Should I be concerned about osteoarticular toxicity in the infant? ANSWER Although there are concerns about the possible risk of osteoarticular toxicity with ciprofloxacin, the amounts excreted into breast milk are low and studies report no substantial increase in osteoarticular toxicity even with the systemic use of ciprofloxacin in neonates and children. Therefore, interrupting breastfeeding during ciprofloxacin treatment appears unnecessary. QUESTION Ma patiente a une infection urinaire et elle allaite actuellement son fils de 9 semaines. Devrais-je m'inquiéter au sujet de la toxicité ostéoarticulaire chez le nouveau-né? RPONSE Même s'il existe des préoccupations entourant le risque possible de toxicité ostéoarticulaire avec la ciprofloxacine, les quantités excrétées dans le lait maternel sont faibles et les études ne signalent aucune augmentation substantielle de la toxicité ostéoarticulaire même avec l'utilisation systémique de la ciprofloxacine chez les nouveau-nés et les enfants. Par conséquent, il ne semble pas nécessaire d'interrompre l'allaitement durant un traitement avec de la ciprofloxacine. Ciprofloxacin is a second-generation, broad-spectrum fluoroquinolone antibiotic with bactericidal activity against Gram-positive and Gram-negative organisms, including those resistant to penicillins, cephalosporins, and aminoglycosides. I think God is warning me to pray punctually and more often. The other four first trimester exposures were an ectopic pregnancy, a spontaneous abortion and two terminations." Oh My God, I had been exposed to ciprofloxacin during the first trimester. I hoped I was not four of the nine women which was explained above. Now, My pregnancy is going 14 weeks and I hope everything will be fine. Five of the nine women who received ciprofloxacin during the first trimester experienced normal births with no reported congenital abnormalities. An observational cohort study looking at human experience with five different antibiotics reported a total of 40 pregnancies with ciprofloxacin. All happening in this world depends on God." According to Qur'an, Surah An Nahl (16), verse 40, "For to anything which We have willed, We but say the word "Be", and it is." Besides, If I got stressed, the fetus would be stressed too. According to Center For Drug Evaluation and Research, "while there are no controlled studies of ciprofloxacin use in pregnant women to show safety, an expert review of published data on experiences with ciprofloxacin use during pregnancy by TERIS - the Teratogen Information System - concluded that therapeutic doses during pregnancy are unlikely to pose a substantial teratogenic risk (quantity and quality of data = fair), but the data are insufficient to state that there is no risk. Then, I gave it to him, and i teased him, " Hey, the result is positive! After that, he looked at the pregnant pack test and he said, " Yes, you're right. While my husband was driving home, I was upset and quiet. You should pray and ask God to have a healthy child. I searched some websites that talked about taking ciprofloxacin while pregnant. He asked me to use pregnancy pack test to find out whether I was pregnant or not. When I saw it at the first time, I thought there was one strip, it meant that It was negative. I said, " It's all up to you, Doc..." I couldn't say anything. "Because there is no treatment for this, I'll give you only vitamins", He said.

    Is ciprofloxacin safe during pregnancy

    Bioterrorism and Drug Preparedness Ciprofloxacin Use by Pregnant., The Hospital for Sick Children - Use of ciprofloxacin during. - Motherisk

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  4. Advice and warnings for the use of Ciprofloxacin during pregnancy. the safety of this drug in pregnant women and their developing fetuses.

    • Ciprofloxacin Use During Pregnancy.
    • Urinary Tract Infections in Pregnancy Treatment & Management..
    • Ciprofloxacin and pregnancy - Daily Trust.

    May 12, 2006. Two weeks later, my husband suspected that I was pregnant, whereas in fact I didn't feel it. studies of ciprofloxacin use in pregnant women to show safety. Five of the nine women who received ciprofloxacin during the first. Ciprofloxacin should be used during pregnancy only if the possible benefit. any unused oral suspension should be safely thrown away. Is ciprofloxacin recommended for use during pregnancy? Ciprofloxacin is. Safety of the new quinolones in pregnancy. Obstet Gynecol.

     
  5. spbel User

    40-60 mg/day PO initially (in single daily dose or divided q12hr for 1 week if patient needs to adjust to therapy) Titrate dose in increments of 30 mg/day over 1 week as tolerated Target dosage: 60 mg/day PO (in single daily dose or divided q12hr); not to exceed 120 mg/day (safety of dosages Treatment of chronic musculoskeletal pain, including discomfort from osteoarthritis and chronic lower back pain 30 mg/day PO initially for 1 week to allow for therapy adjustment Target dosage: 60 mg/day PO; not to exceed 60 mg/day Dosages ≥60 mg/day have not been shown to offer additional benefits Major depressive disorder and generalized anxiety disorder: Acute episodes often necessitate several months of sustained therapy Diabetic peripheral neuropathic pain: Efficacy for 12 weeks has not been studied; if diabetes is complicated by renal disease, consider lower starting dosage with gradual increase to effective dosage Fibromyalgia: Efficacy for ≥12 weeks has not been studied; continue treatment on basis of individual patient response Chronic musculoskeletal pain: Efficacy for ≥13 weeks has not been studied Uncontrolled narrow-angle glaucoma: Use not recommended due to increased risk of mydriasis Constipation (10%) Dizziness (10%) Insomnia (10%) Diarrhea (9-10%) Anorexia (8%) Decreased appetite (7-8%) Abdominal pain (6%) Hyperhidrosis (6%) Increased sweating (6%) Agitation (5%) Nasopharyngitis (5%) Vomiting (3-5%) Male sexual dysfunction (2-5%) Abdominal pain (4%) Decreased libido (4%) Musculoskeletal pain (4%) Upper respiratory tract infection (URTI) (4%) Abnormal orgasm (3%) Agitation (3%) Anxiety (3%) Blurred vision (3%) Cough (3%) Influenza (3%) Muscle spasms (3%) Tremor (3%) Abnormal dreams (2%) Dyspepsia (2%) Hot flushes (2%) Nausea (2%) Oropharyngeal pain (2%) Palpitations (2%) Paresthesia (2%) Weight loss (2%) Yawning (2%) Dysuria ( General: Anaphylactic reaction, angioneurotic edema, hypersensitivity Cardiovascular: Hypertensive crisis, supraventricular arrhythmia, myocardial infarction, tachycardia, Takotsubo cardiomyopathy Endocrine: Galactorrhea, gynecologic bleeding, hyperglycemia, hyperprolactinemia Neurologic: Restless legs syndrome, seizures upon treatment discontinuance, extrapyramidal disorders Ophthalmic: Glaucoma Otic: Tinnitus (upon treatment discontinuance) Psychiatric: Aggression and anger (particularly early in treatment or after treatment discontinuance), hallucinations Musculoskeletal: Trismus, muscle spasm Skin: Serious skin reactions (eg, erythema multiforme and Stevens-Johnson syndrome) necessitating drug discontinuance or hospitalization, urticaria, rash Gastrointestinal: Colitis (microscopic or unspecified),cutaneous vasculitis (sometimes associated with systemic involvement), acute pancreatitis Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term studies These studies did not show an increase in the risk of suicidal thoughts and behavior with antidepressant use in patients 24 yr There was a reduction in risk with antidepressant use in patients ≥65 yr In patients of all ages who are started on antidepressant therapy, monitor closely for worsening, and for emergence of suicidal thoughts and behaviors Advise families and caregivers of the need for close observation and communication with the prescriber CYP1A2 inhibitors or thioridazine should not be coadministered Use caution in severe renal impairment, ESRD Heavy alcohol use Suicidality; monitor for clinical worsening and suicide risk, especially in children, adolescents and young adults (18-24 years) during early phases of treatment and alterations in dosage Serotonin syndrome or neuroleptic malignant syndrome-like reactions may occur; discontinue and initiate supportive therapy; closely monitor patients concomitantly receiving triptans, antipsychotics and serotonin precursors Neonates exposed to serotonin-noreponephrine reuptake inhibitors (SNRIs) or selective serotonin reuptake inhibitors (SSRIs) late in 3rd trimester of pregnancy have developed complications necessitating prolonged hospitalization, respiratory support, and tube feeding Screen patients for bipolar disorder; risk of mixed/manic episodes is increased in patients treated with antidepressants May cause activation of mania or hypomania Increased risk of hepatotoxicity, sometimes fatal; monitor for abdominal pain, hepatomegaly, elevations in hepatic transaminases exceeding 20 times upper limit of normal; jaundice; cholestatic jaundice with minimal elevations of hepatic transaminases have also been reported; use not recommended in patients with substantial alcohol use or chronic liver disease SSRIs and SNRIs may impair platelet aggregation and increase the risk of bleeding events, ranging from ecchymoses, hematomas, epistaxis, petechiae, and GI hemorrhage to life-threatening hemorrhage; concomitant use of aspirin, NSAIDs, warfarin, other anticoagulants, or other drugs known to affect platelet function may add to this risk Severe skin reactions (eg, erythema multiforme and Stevens-Johnson syndrome); discontinue at first appearance of blisters, peeling rash, mucosal erosions, or any other sign of hypersensitivity if no other etiology can be identified Orthostatic hypotension and syncope, especially during week 1 of therapy; monitor patients taking drugs that increase risk of orthostatic hypotension; consider dose reduction or discontinue therapy in patients who experience symptomatic orthostatic hypotension, falls and/or syncope Hyponatremia due to syndrome of inappropriate antidiuretic hormone (SIADH); cases of serum sodium Exact mechanism of action unknown; inhibits reuptake of serotonin and norepinephrine; weakly inhibits reuptake of dopamine; has no MAOI activity; has no significant activity for histaminergic H1 receptor or alpha2-adrenergic receptor The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information. Duloxetine Oral Route Proper Use - Mayo Clinic Duloxetine Uses, Side Effects, Dosage, Warnings - Cymbalta Duloxetine Hcl Patient Information Side Effects and.
     
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